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Harmful Algae & Red Tide Species Information

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Pseudo-nitzschia spp.

Potential Toxin Produced: Domoic Acid
Syndrome: Amnesic shellfish poisoning (ASP)
Photo courtesy of Dr. Rozalind Jester

Some species of the marine diatom, Pseudo-nitzschia, can produce domoic acid (DA), a naturally occurring but rare amino acid that is toxic to marine mammals and seabirds, as well as to humans. Affected individuals mostly experience gastrointestinal disorders and neurological problems. One of the primary symptoms, amnesia, led to the naming of the syndrome as amnesic shellfish poisoning (ASP).

Domoic acid was first associated with phytoplankton as a source of the toxin in 1987, when over 100 people were sickened and three died following consumption of DA-contaminated mussels from eastern Prince Edward Island, Canada. In California, DA was first recognized in September 1991 in Monterey Bay, when the deaths of more than 100 brown pelicans and cormorants were linked to DA poisoning. Since then, the toxin has been implicated in other deaths of marine mammals and seabirds between Monterey Bay and San Diego.

At least nine species within the marine diatom genus Pseudo-nitzschia are now known to produce DA. In California, Pseudo-nitzschia australis and Pseudo-nitzschia multiseries are the main toxin producers.

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